Specific medical conditions of known cause or origin, which can often be documented by physical signs and laboratory findings.  BRI includes:

• sensory irritation when caused by known agents

• respiratory allergies

• nosocomial infections

• humidifier fever

• hypersensitivity pneumonitis

• Legionnaires' disease

• symptoms and signs consistent with exposure to chemical or biological substances (CO, formaldehyde, pesticides, endotoxins, mycotoxins)