In tropical countries, diseases caused by ingestion of fungal toxins are among leading causes of death

liver cancer from ingestion of aflatoxins

esophageal cancer caused by Fusarium toxins

indirect cause of death from excessive consumption of immune system depressors such as trichothecenes

Very rare in temperate and cold-weather climates

Hazards associated with inhalation exposure

infectious diseases: histoplasmosis, aspergillosis

allergy: growing segment of our population

hypersensitivity diseases: (e.g., HP - hypersensitivity pneumonitis) typically from exposure to very high concentrations of organic dusts; permanent lung damage can occur

mycotoxicoses:  organic dust toxic syndrome (ODTS) from massive exposures;  limited data on the long-term effects of chronic, low doses of inhaled mycotoxins

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